Research
CIRCADIAN Light Research Center: Optimizing Light for Human Health and Performance
Dr Martin Moore-Ede, a former professor at Harvard Medical School, and his biomedical and engineering research teams built the Circadian Light Research Center in 2010 as a specialized research facility to identify and develop the optimal lighting for day and night. With funding from the National Institutes of Health and other sources they operated this light-controlled medical research center with fully spectrally-controlled workplace and residential lighting, to study the impacts of LED and other lighting on human volunteers living and working shifts around the clock.
As lighting with carefully controlled spectral content is delivered, a full range of physiological, psychological performance and medical tests are undertaken including:
- Sleep and wakefulness with continuous EEG monitoring
- Blood tests (lipids, cardiac markers)
- Glucose Tolerance tests (Diabetes)
- 24-hour urine melatonin collection
- Salivary Melatonin 30-minute intervals
- Blood pressure
- Alertness & performance tests
- Mood and Depression scale test
Full ethical protection of our volunteers is provided. Each participant gave written informed consent after receiving a full explanation of the study purpose, design, and procedures. Study protocols and consent forms are reviewed and approved by the Circadian Institutional Review Board (IRB# 00001522) registered for Federal Wide Assurance (FWA) with the Office for Human Research Protections (OHRP) of the Department of Health and Human Services (HHS).
The Circadian Light Research Center also conducts studies and evaluates lighting products that meet the rigorous standards of evidence-based circadian lighting.

Recent Publications
Lights Should Support Circadian Rhythms: Evidence-based Scientific Consensus
OCTOBER 4, 2023 Frontiers in Photonics (2023) 4:1272934
INDUSTRY INSIGHTS | How the industry can standardize circadian lighting
APRIL 24, 2023 LEDs Magazine
Circadian Potency Spectrum in Light-Adapted Humans
AUGUST 18, 2022 Cell Sci Therapy. 13:361-366 (2022)
LEDs must spectrally balance illumination, circadian health, productivity, and energy efficiency
APRIL 30, 2021 LEDs Magazine: April 30, 2021
Circadian Potency Spectrum with Extended Exposure to Polychromatic White LED Light Under Workplace Conditions
JUNE 16, 2020 Biol Rhythms 35(4): 405–415 (2020)